Peer-reviewed veterinary case report
Photodynamic therapy tried for wing cancer in African rose-ringed
By Suedmeyer, Wm Kirk et al.·Published in Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians·2007·Kansas City Zoo, United States·View original on PubMed →
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Original publication title: Attempted photodynamic therapy against patagial squamous cell carcinoma in an African rose-ringed parakeet (Psittacula krameri).
- Species:
- bird
Plain-English summary
A 5-year-old female African rose-ringed parakeet was brought in with an ulcerated mass on her right wing. A biopsy revealed that the mass was a squamous cell carcinoma, a type of skin cancer. The bird underwent photodynamic therapy, which initially reduced the size of the tumor, but unfortunately, it did not completely eliminate it. This case suggests that the standard photodynamic therapy protocols used for dogs, cats, and humans may not be effective for birds, indicating a need for tailored approaches in avian cancer treatment.
People also search for: parakeet tumor treatment · squamous cell carcinoma in birds · photodynamic therapy for avian cancer
Abstract
A 5-yr-old female African rose-ringed parakeet (Psittacula krameri) presented with an ulcerated mass in the medial postpatagial area of the right wing. Biopsy specimens of the mass demonstrated a well-differentiated squamous cell carcinoma. Photodynamic therapy resulted in tumor cell necrosis and initial reduction in tumor burden, but complete remission was not achieved. Based on this and other avian cases, it appears that photodynamic therapy designed to eradicate squamous cell carcinoma in avian species using protocols modeled after canine, feline, and human photodynamic therapy protocols may not be useful. It is hypothesized that differences in light penetration, photosensitizing agent pharmacokinetics, and wound healing properties in avian species necessitate alteration of photodynamic therapy protocols if this treatment modality is to be effective in avian oncology.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18229870/