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Peer-reviewed veterinary case report

Cat skin nodules from sporotrichosis that look like vaccine sarcoma

By dos Santos, Isabele Barbieri et al.·Published in Journal of feline medicine and surgery·2013·Laboratory for Clinical Research on Dermatozoonoses in Domestic Animals, Brazil·View original on PubMed

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Original publication title: Atypical feline sporotrichosis resembling vaccine-induced sarcoma: clinical and histopathological aspects.

Species:
cat

Plain-English summary

A 7-year-old Siamese cat was brought in with three ulcerated lumps on its lower back that looked like they could be caused by a vaccine reaction. Tests showed that the lumps were actually caused by a fungal infection called sporotrichosis, which is caused by the fungus Sporothrix schenckii. This diagnosis was confirmed through special staining techniques and a culture test. The cat's treatment would likely involve antifungal medication to help clear the infection.

People also search for: cat skin lumps treatment · Siamese cat ulcerated nodules · sporotrichosis in cats · vaccine reaction in cats · cat fungal infection symptoms

Abstract

A 7-year-old Siamese cat presenting with three ulcerated cutaneous nodules in the lumbosacral region was seen at the Laboratory for Clinical Research on Dermatozoonoses in Domestic Animals in Rio de Janeiro, Brazil. Histopathological analysis showed that the lesions consisted of polyhedral and spindle-shaped voluminous mononuclear cells with loose chromatin and clearly visible nucleoli, few giant cells, and foci of coagulative and caseous necrosis -- findings suggestive of a vaccine-induced sarcoma. No significant mitotic rate, cytological atypias or asteroid bodies were observed. Special histopathological staining with periodic acid-Schiff and Grocott's silver stain demonstrated the presence of small yeast cells characterized by simple and narrow-base budding compatible with Sporothrix schenckii. Mycological culture grew S schenckii. Cytopathology was negative for yeast cells. These atypical clinical and histopathological signs support the importance of histopathological analysis with special staining techniques, in addition to mycological culture in the diagnosis of feline sporotrichosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23264613/