Peer-reviewed veterinary case report
Dog with atypical hypoadrenocorticism and normal adrenal zona
By Hatoya, Shingo et al.·Published in The Journal of veterinary medical science·2023·Graduate School of Life and Environmental Sciences, Japan·View original on PubMed →
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Original publication title: Atypical hypoadrenocorticism with intact zona glomerulosa of the adrenal cortex after long-term observation: a case report of a dog.
- Species:
- dog
Plain-English summary
An 8-year-old male pointer was brought to the vet because he was lethargic and had low protein levels in his blood. An ultrasound showed that both of his adrenal glands were smaller than normal. After running some tests, the vet diagnosed him with atypical hypoadrenocorticism (a condition affecting hormone production) and started treatment with low-dose prednisolone, which helped improve his overall health and normalized his blood tests. Unfortunately, the dog passed away 818 days later, but an autopsy revealed that while some parts of his adrenal glands were damaged, one area remained mostly normal.
People also search for: dog lethargy causes · atypical hypoadrenocorticism treatment · low protein in dog blood
Abstract
An 8-year-old intact male pointer presented with lethargy and hypoalbuminemia. On abdominal ultrasonography, both adrenal glands were reduced in thickness. Based on the ACTH stimulation test results and the absence of electrolyte abnormalities, the dog was diagnosed with atypical hypoadrenocorticism. After treatment with low-dose prednisolone, his general condition improved, and blood tests normalized. The dog died 818 days later, and a complete autopsy was performed. Histologically, the architecture of the zonae fasciculata and reticularis was disrupted in both adrenal glands; however, the zona glomerulosa remained relatively normal. In summary, in this study, we detailed the pathological presentation of atypical hypoadrenocorticism without electrolyte abnormalities.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36372430/