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Peer-reviewed veterinary case report

Atypical Mpox Cutaneous Presentation After Full Vaccination.

Journal:
The American Journal of dermatopathology
Year:
2025
Authors:
Schreidah, Celine M et al.
Affiliation:
Columbia University Vagelos College of Physicians & Surgeons · United States

Abstract

In 2022-2023 mpox outbreak led to declaration of a public health emergency. Smallpox vaccination has led to increased immunity and a decrease in clinical disease. The role of vaccination in immunosuppressed patients is not well understood. We present an atypical case of cutaneous mpox, presenting in a fully vaccinated, immunosuppressed, HIV-negative patient as an initial isolated, subcutaneous neck mass. We review the diagnostic dilemma and workup for these atypical cases.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/39983067/