Peer-reviewed veterinary case report
Dog with chronic spinal injury treated with bone marrow cell
By Tamura, Katsutoshi et al.·Published in Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation·2015·From the Department of Bioartificial Organs, Japan·View original on PubMed →
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Original publication title: Autologous bone marrow mononuclear cell transplant and surgical decompression in a dog with chronic spinal cord injury.
- Species:
- dog
Plain-English summary
A dog with paraplegia and no feeling in his back legs for three years due to a severe spinal cord injury underwent a special treatment called an autologous bone marrow mononuclear cell transplant. Before the procedure, tests showed no nerve signals, but afterward, some signals returned, indicating improvement. The dog's functional ability also increased significantly on a recovery scale after the treatment, and there were no negative side effects. This suggests that this type of transplant could be a safe and helpful option for dogs with long-term spinal cord injuries.
People also search for: dog paraplegia treatment · spinal cord injury in dogs · bone marrow transplant for dogs
Abstract
OBJECTIVES: In dogs with deep analgesia caused by acute spinal cord injury from thoracolumbar disk herniation, autologous bone marrow mononuclear cell transplant may improve recovery. The purpose of the present study was to evaluate autologous bone marrow mononuclear cell transplant in a dog that had paraplegia and deep analgesia caused by chronic spinal cord injury. MATERIALS AND METHODS: Autologous bone marrow mononuclear cell transplant was performed in a dog having paraplegia and analgesia for 3 years that was caused by a chronic spinal cord injury secondary to Hansen type I thoracolumbar disk herniation. Functional recovery was evaluated with electrophysiologic studies and the Texas Spinal Cord Injury Scale. RESULTS: Somatosensory evoked potentials were absent before transplant but were detected after transplant. Functional improvement was noted (Texas Spinal Cord Injury Scale: before transplant, 0; after transplant, 6). No adverse events were observed. CONCLUSIONS: Autologous bone marrow mononuclear cell transplant into the subarachnoid space may be a safe and beneficial treatment for chronic spinal cord injury in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25019162/