Peer-reviewed veterinary case report
Stem cell joint treatment for dogs with bad knee and hip arthritis
By Schroers, M et al.·Published in Australian veterinary journal·2024·Clinic for Small Animal Surgery and Reproduction, Germany·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Autologous point-of-care stromal vascular fraction transplantation in dogs with advanced osteoarthritis of the knee and hip joints.
- Species:
- dog
Plain-English summary
A group of dogs with advanced arthritis in their knees and hips underwent a new treatment where fat was taken from their own bodies and processed to help relieve pain and improve movement. After the procedure, some owners reported that their pets showed less limping and seemed to feel better, with three out of five dogs with knee arthritis and two out of four with hip arthritis improving. However, detailed movement tests only showed improvement in two dogs over a three-month period. While this treatment may help some dogs, the benefits appear to be short-lived, raising questions about its overall value.
People also search for: dog knee arthritis treatment · hip arthritis in dogs · stem cell therapy for dogs arthritis
Abstract
OBJECTIVE: The aim of the study was to assess lameness in dogs with advanced osteoarthritis of the hip and knee joints after a single autologous point-of-care transplantation of the Stromal Vascular Fraction (SVF) into the affected joint. MATERIALS AND METHODS: During a minilaparotomy, 10 g of falciform fat was removed from each patient for each joint to be treated. A modern and time-saving procedure (ARC TM System, InGeneron GmbH, Houston, USA) was used for the in-house preparation of the SVF, so that the isolated cells could be applied to the respective joint within 2 h after fat removal. In total, five knee joints of five patients and seven hip joints of four patients were treated. RESULTS: Improvement in lameness according to owner questionnaires was seen in 3 of 5 patients with knee joint arthritis and 2 of 4 patients with hip joint arthritis. Based on gait analysis, only one dog with gonarthrosis and one dog with coxarthrosis showed improvement up to a maximum of 3 months after surgery. CONCLUSION: This is the first case series on the treatment of osteoarthrosis of the knee or hip joint using point-of-care transplantation of the SVF. In individual cases, this method may represent a therapeutic approach for the treatment in dogs with advanced cox- or gonarthrosis, although only a short-term effect can be expected, which calls into question the effort and costs involved.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38044819/