Peer-reviewed veterinary case report
Autologous tissue repair for pelvic organ prolapse in women overview
By Alao AI et al.·2026·Specialty Registrar ST7, United Kingdom·View original on Europe PMC →
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Original publication title: Autologous tissue sacrocolpopexy for apical pelvic organ prolapse: a scoping review of the extent, nature, and characteristics of the evidence.
Plain-English summary
This review looked at a surgical procedure called autologous-tissue sacrocolpopexy, which uses the patient's own tissue to treat a condition where pelvic organs drop down (apical pelvic organ prolapse). The researchers examined 11 studies involving 311 women, with follow-up periods ranging from about 10 to 60 months. They found that the success rate of the surgery varied widely, from 75% to 100%, but some women experienced new issues with urinary incontinence after the procedure. Overall, the studies were mostly small and did not provide enough long-term data or comparisons to other surgical options, so more research is needed to fully understand the effectiveness and safety of this approach.
Abstract
<h4>Introduction</h4>Mesh sacrocolpopexy is effective but carries mesh-specific risks. Interest in autologous-tissue sacrocolpopexy using autologous grafts has grown, but its effectiveness and perioperative profile are less clear. This scoping review aimed to map the extent, range, and nature of research on autologous-tissue sacrocolpopexy for apical prolapse, identify knowledge gaps, and summarise reported outcomes and complications.<h4>Methods</h4>Two reviewers independently screened and extracted data in duplicate; a third reviewer resolved disagreements. We mapped 11 studies (n = 311 women). Thematic synthesis was performed; no meta-analysis was conducted.<h4>Results</h4>Eleven studies were included (311 women; sample size range 4-132). Designs were one randomised controlled trial and ten single-arm series; follow-up ranged from about 10 to 60 months. Seven studies used fascia lata and four used rectus fascia; procedures were mainly open with five robotic series. The success rate ranged from 75% to 100%. De novo stress urinary incontinence ranged from 8.3% to 32.5% where reported; de novo urgency urinary incontinence ranged from 0% to 35.6%.<h4>Conclusion</h4>The available literature is limited to small, mostly single-arm studies with short- to medium-term follow-up. Key gaps include a lack of direct comparative trials with mesh, long-term durability data, and standardised outcome reporting.
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Search related cases →Original publication on Europe PMC: https://europepmc.org/article/MED/42019134