Peer-reviewed veterinary case report
Rhodesian ridgeback ridge gene raises risk of dermoid sinus skin
By Hillbertz, N H C Salmon & Andersson, G·Published in The Journal of small animal practice·2006·Department of Animal Breeding and Genetics·View original on PubMed →
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Original publication title: Autosomal dominant mutation causing the dorsal ridge predisposes for dermoid sinus in Rhodesian ridgeback dogs.
- Species:
- dog
Plain-English summary
Rhodesian Ridgeback dogs with the characteristic dorsal ridge are at a higher risk of developing a congenital skin condition called dermoid sinus. This condition can lead to skin infections and other complications if not treated. The study found that the trait for the ridge is inherited in an autosomal dominant manner, meaning that if a dog has the ridge, it can pass it on to its puppies. Pet owners should be aware of this risk and consult their veterinarian for monitoring and potential treatment options if their Ridgeback shows any signs of skin issues.
People also search for: Rhodesian Ridgeback skin problems · dermoid sinus treatment in dogs · congenital skin conditions in dogs
Abstract
OBJECTIVES: To define the mode of inheritance of the dorsal ridge and investigate if the ridge predisposes to the congenital abnormality dermoid sinus in the Rhodesian ridgeback. METHODS: Segregation analysis was performed, including 87 litters (n=803) produced in Sweden between 1981 and 2002. Data were corrected to avoid bias in the segregation ratio. Chi-squared analysis was performed including 402 litters (n=3598) for the evaluation of a possible genetic correlation between the ridge and dermoid sinus. RESULTS: The ridge is inherited in an autosomal dominant mode and predisposes for dermoid sinus. The frequency of ridgeless offspring in the Swedish Rhodesian ridgeback population is estimated to be 5.6 per cent. CLINICAL SIGNIFICANCE: Rhodesian ridgeback dogs that carry the ridge trait are predisposed to dermoid sinus.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16573760/