Peer-reviewed veterinary case report
Avian riboflavin deficiency: an acquired tomaculous neuropathy.
- Journal:
- Veterinary pathology
- Year:
- 2006
- Authors:
- Cai, Z et al.
- Affiliation:
- Hanson Institute Centre for Neurological Diseases · Australia
- Species:
- bird
Abstract
The finding of tomacula, focal areas of sausage-shaped hypermyelination in peripheral nerves, is reported for the first time in avian riboflavin deficiency. Day-old, meat-type chickens were fed a riboflavin-deficient diet (1.8 mg/kg) and were killed on postnatal days 6, 11, 16, and 21, while control chickens were fed a conventional diet containing 5.0 mg/kg riboflavin. Tomacula were found in sciatic and brachial nerves from day 11 onward, became more frequent and prominent with increasing time, and preceded the onset of segmental demyelination.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16966461/