Peer-reviewed veterinary case report
Babesia gibsoni: identification of an immunodominant, interspersed repeat antigen.
- Journal:
- Experimental parasitology
- Year:
- 2008
- Authors:
- Jia, Honglin et al.
- Affiliation:
- Obihiro University of Agriculture and Veterinary Medicine · Japan
- Species:
- dog
Abstract
In this report, an immunodominant antigen called BgIRA from Babesia gibsoni is identified and described. A highly repetitive antigen was screened from a cDNA library. The genomic BgIRA gene exists as single cope gene and contains 10 introns. BgIRA plays a dominant role in the immune response in dogs infected with B. gibsoni. The specificity and sensitivity of the rBgIRA in an ELISA indicated that this antigen might be useful in a diagnostic test.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17870070/