Babesia ovata: Taxonomy, phylogeny and epidemiology.

Abstract

Babesia ovata, which is transmitted by Haemaphysalis longicornis, is an intraerythrocytic protozoan parasite of cattle. Based on its morphology, B. ovata is classified as a large-type Babesia. The developmental stages of B. ovata have been described both in cattle and the tick vector. In infected adult female ticks, the parasite is transovarially transmitted to the tick eggs. The sexual reproduction of B. ovata has been demonstrated in the tick midgut. The diagnostic tools that are currently available for the specific detection of B. ovata in cattle include microscopy and polymerase chain reaction assays. The development of improved molecular and serological diagnostic tools has been constrained by the limited availability of genetic data. B. ovata has been reported in cattle populations in Japan, Korea, China, Mongolia and Thailand. B. ovata was thought to be a benign parasite; however, infections in immuno compromised or Theileria orientalis-infected animals are clinically significant. Thus, control strategies aimed at minimizing the prevalence of B. ovata are vital. The taxonomy of B. ovata is unclear, and the phylogenetic position has not been well defined. Consequently, non-B. ovata species have sometimes been classified as B. ovata. In this review, we provide an outline of the lifecycle, geographical distribution, and control of B. ovata, and critically discuss the taxonomy and phylogeny of this bovine Babesia.