Peer-reviewed veterinary case report
Cat with bone fusions from vitamin A overdose without spine damage
By Franch, J et al.·Published in Journal of feline medicine and surgery·2000·Veterinary School of Barcelona, Spain·View original on PubMed →
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Original publication title: Back-scattered electron imaging of a non-vertebral case of hypervitaminosis A in a cat.
- Species:
- cat
Plain-English summary
A cat suffered from hypervitaminosis A, which is a condition caused by too much vitamin A, leading to serious joint problems. The cat developed bony fusions in both hip and knee joints, making movement difficult. Unfortunately, the cat passed away, and a post-mortem examination showed abnormal bone growth around the joints. This condition can cause significant discomfort and mobility issues in pets. If you notice similar symptoms in your cat, such as difficulty moving or joint swelling, it's important to consult your veterinarian for advice and potential treatment options.
Abstract
We describe a clinical case of hypervitaminosis A in a cat. The main lesions were bony fusions of both the hip and stifle joints, without spinal involvement. A post-mortem study using back-scattered scanning electron microscopy (BEI-SEM) revealed that exostoses had formed around the joints without articular surface involvement. The more recently formed areas of bony proliferation were composed mainly of chondroid tissue surrounded by different degrees of woven bone. As the bony reaction occurred, remodelling of the trabeculae was observed which lead to progressive substitution of chondroid tissue by woven bone surrounded by apposition of lamellar bone. No traces of calcified cartilage were observed in any of the bone sections evaluated.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11716591/