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Peer-reviewed veterinary case report

Baicalein exerts a protective role in pneumonia caused by.

Journal:
Frontiers in bioscience (Landmark edition)
Year:
2019
Authors:
Qinghe, Guo et al.
Affiliation:
School of Laboratory Medicine · China
Species:
rodent

Abstract

is the most common pathogenic bacterium of pneumonia and can cause death. Here, we examined the impact of Baicalein on mouse mortality caused byinfection. Baicalein protected mice from-induced deaths. Baicalein reduced alveolocapillary membrane permeability, lung infiltration of inflammatory cells, inflammatory cytokine production and pulmonary cell apoptosis. These evidences show that Baicalein is useful in the therapy of a severe form of pneumonia that can cause deaths.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30844717/