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Peer-reviewed veterinary case report

Behavioral model for assessing cognitive decline.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2012
Authors:
Guidi, Michael & Foster, Thomas C
Affiliation:
Max Planck Institute of Psychiatry · Germany

Abstract

The water maze task can be used to assess sensory motor and cognitive function in rodents. When properly employed, this task can behaviorally assess acquisition of a spatial search strategy, as well as working and reference memory. The following section uses research on age-related, cognitive decline to illustrate the methods employed and highlight areas that can, if not properly controlled, confound a study.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22231811/