Bergeyella zoohelcum: A first case report of its association with respiratory diseases in swine in China.

Abstract

The current investigation presents the first case report of Bergeyella zoohelcum associated with respiratory tract infections in pigs in China. Two Gram-negative bacterial isolates with bacillus morphology were isolated from the heart and lung samples of two pigs having respiratory symptoms in two separate cases. The isolates were identified as B. zoohelcum using morphological, biochemical, and molecular approaches, including 16 S rRNA sequencing. Antimicrobial susceptibility test (AST) revealed that the B. zoohelcum isolates exhibit multi-drug resistance (MDR) patterns, particularly the B. zoohelcum ZWSF strain, which showed resistance to several antibiotics including polymyxin B, tetracycline, chloramphenicol, erythromycin, fosfomycin, amikacin, and gentamicin. Therefore, further investigations are necessary to better understand the pathogenicity of B. zoohelcum in swine and to prevent its spread.