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Peer-reviewed veterinary case report

Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1.

Journal:
Antimicrobial agents and chemotherapy
Year:
2007
Authors:
San Millan, Alvaro et al.
Affiliation:
Departamento de Sanidad Animal · Spain

Abstract

beta-Lactam resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. Clinical high-level beta-lactam-resistant isolates from Spain bore a novel plasmid, pB1000, expressing a functionally active ROB-1 beta-lactamase. Pulsed-field gel electrophoresis was applied for the first time to H. parasuis and showed that beta-lactam resistance is due to clonal spread of a resistant strain, BB1018, bearing pB1000.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17438055/