Peer-reviewed veterinary case report
Bilateral common carotid artery occlusion as an adequate preconditioning stimulus to induce early ischemic tolerance to focal cerebral ischemia.
- Journal:
- Journal of visualized experiments : JoVE
- Year:
- 2013
- Authors:
- Speetzen, Lukas Julius et al.
- Affiliation:
- Department of Neurology · Germany
- Species:
- rodent
Abstract
There is accumulating evidence, that ischemic preconditioning - a non-damaging ischemic challenge to the brain - confers a transient protection to a subsequent damaging ischemic insult. We have established bilateral common carotid artery occlusion as a preconditioning stimulus to induce early ischemic tolerance to transient focal cerebral ischemia in C57Bl6/J mice. In this video, we will demonstrate the methodology used for this study.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23685461/