Peer-reviewed veterinary case report
Cat with seizures caused by brain blood vessel disease on both sides
By Kipar, A et al.·Published in Veterinary pathology·2001·Institut fü, Germany·View original on PubMed →
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Original publication title: Bilateral focal cerebral angiomatosis associated with nervous signs in a cat.
- Species:
- cat
Plain-English summary
A 5-year-old domestic shorthair cat was brought in for severe seizures that occurred in clusters. The veterinarian discovered that the cat had a rare condition called cerebral angiomatosis, which involves abnormal blood vessel growth in the brain. This condition caused narrowing and blockage of blood vessels, leading to the seizures. Unfortunately, the specific treatment for this condition isn't well established, and the cat's prognosis may vary depending on the severity of the symptoms.
People also search for: cat seizures treatment · why is my cat having seizures · cat brain problems · cat neurologic signs · cerebral angiomatosis in cats
Abstract
A case of cerebral angiomatosis in a cat was associated with neurologic signs characterized by clusters of severe generalized seizures. Bilaterally in the gray matter, most prominent in the cingulate gyrus, there was focal accumulation of garlandlike arrangements of blood vessels. Vessels exhibited activated, hypertrophic endothelial cells and thickening and progressive dystrophic mineralization of the basement membrane, with complete luminal obstruction of some affected vessels. Thickening of the basement membrane was due to accumulation of endothelium-derived proteins such as laminin and von Willebrand factor. Furthermore, moderate diffuse astrogliosis was observed. Findings indicate an idiopathic angiomatosis, with clinical signs possibly due to ischemia resulting from narrowing or complete obliteration of vessel lumina. Changes represent a unique endothelial cell-derived lesion within the brain not previously described in humans or domestic animals.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11355671/