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Peer-reviewed veterinary case report

Bilateral intraocular glandular choristomas in a Thoroughbred foal.

Journal:
Veterinary ophthalmology
Year:
2009
Authors:
Baumgartner, Wes A et al.
Affiliation:
Louisiana State University School of Veterinary Medicine · United States
Species:
horse

Plain-English summary

A Thoroughbred foal was brought in because of problems with its eyes. The foal had several serious eye issues, including small eyes, abnormal growths on the cornea, and other developmental problems. Tests showed that the unusual tissue growths in the eye were similar to those found in the tear glands of normal horses. This suggests that the abnormal tissue in the foal's eye likely came from the tear glands. The treatment details and outcome were not provided in the study.

Abstract

Intraocular choristomas are rare anomalies in domestic animals and are often associated with multiple ocular malformations. A Thoroughbred foal presented for ocular abnormalities and was diagnosed with microphthalmia, corneal dermoids, severe anterior segment dysgenesis (including glandular choristomas), aphakia, retinal dysplasia, and optic nerve hypoplasia. Morphological, histochemical, and immunohistochemical comparisons were made between ocular choristomatous tissues from this foal and lacrimal gland, third eyelid gland, nasopharynx, trachea, and lacrimal sac/nasolacrimal duct from normal horses. Morphologically the choristomatous tissues (glands and epithelium lining the anterior segment) were most similar to the lacrimal sac. Histochemistry of glandular components found the glands associated with the lacrimal sac/nasolacrimal duct to be serous, as was the glandular intraocular choristomas. Our findings suggest that the origin of intraocular glandular choristomas in this case is from the lacrimal sac.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19261166/