Peer-reviewed veterinary case report
Cat with brain swelling and blood vessel damage in both hemispheres
By Morita, T et al.·Published in Journal of comparative pathology·2003·Department of Veterinary Pathology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Bilateral oedema with angiopathy in the dorsointernal area of the cerebral hemispheres of a domestic cat.
- Species:
- cat
Plain-English summary
A domestic cat suddenly developed a high fever and severe neck arching (opisthotonus), and unfortunately, passed away just one day later. Upon examination, the vet found swelling in the brain and damage to the blood vessels. This case is notable because it highlights a rare type of brain swelling in cats that affects both sides of the brain. Sadly, the cat did not survive, but this report helps veterinarians understand this serious condition better.
People also search for: cat fever and neck arching · cat brain swelling symptoms · causes of cat sudden death
Abstract
This report describes a feline case of oedema and angiopathy associated with the sudden onset of pyrexia and opisthotonus, followed by death one day later. Histologically, oedema and vascular lesions were found bilaterally in the dorso-internal area of the cerebral hemispheres. The vascular lesions consisted of perivascular exudation of periodic acid-Schiff-positive eosinophilic material and hyaline degeneration of the vascular walls. Immunohistochemically, the perivascular material reacted with anti-fibrinogen antibody; weak labelling for laminin was occasionally seen in the basement membranes of affected capillaries, arterioles and venules, in contrast to the strong labelling seen in the normal brain. Ultrastructurally, serum protein was observed in the space between the basement membranes of capillary endothelial cells and astrocytes, and vascular basement membranes were occasionally thickened. This is, to our knowledge, the first report of feline vasogenic oedema with a bilateral distribution in the cerebrum.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12921730/