Peer-reviewed veterinary case report
Cat with rapidly growing thyroid tumors on both sides
By Rich, A F et al.·Published in Journal of comparative pathology·2019·Department of Veterinary Pathology and Public Health, United Kingdom·View original on PubMed →
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Original publication title: Bilateral Thyroid Carcinosarcoma in a Cat.
- Species:
- cat
Plain-English summary
A neutered female domestic shorthaired cat was brought in for a rapidly growing mass on the left side of her neck and had been diagnosed with hyperthyroidism for six months. Unfortunately, despite treatment, her condition worsened, leading to her being humanely euthanized. A post-mortem examination revealed that she had bilateral thyroid carcinosarcomas, which are rare tumors affecting the thyroid gland. The cat also had a separate lung tumor, but it was not related to the thyroid issue.
People also search for: cat neck mass · hyperthyroidism in cats · cat thyroid cancer symptoms · what is thyroid carcinosarcoma in cats · cat lung tumor treatment
Abstract
A neutered female domestic shorthaired cat was presented for a rapidly growing left cervical mass and a 6-month history of primary hyperthyroidism. Cytological examination of the mass was consistent with a sarcoma. Due to poor clinical response the cat was humanely destroyed and a post-mortem examination was performed. This revealed a markedly enlarged, irregularly shaped left thyroid gland with signs of infiltration of the trachea. The contralateral (right) thyroid was also moderately enlarged and irregularly shaped. Histopathological examination of the cervical masses indicated bilateral thyroid carcinosarcomas, evidenced by positive immunohistochemical labelling for vimentin, pan-cytokeratin and thyroid transcription factor-1 of the appropriate cell populations. The cat also had a concurrent pulmonary adenocarcinoma (papillary-lepidic type), unrelated to the thyroid neoplasm. Thyroid carcinosarcoma is an uncommonly recorded canine and human neoplasm and this is the first case of this entity to be reported in a cat.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31540622/