Peer-reviewed veterinary case report
Bioluminescent Imaging of Patient-Derived Brain Tumors in Live Mice.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2025
- Authors:
- McKenna, Dillon et al.
- Affiliation:
- McMaster University · Canada
- Species:
- rodent
Abstract
Patient-derived tumor xenograft (PDX) models are crucial for understanding brain tumor progression and for pre-clinical evaluation of therapeutic interventions. Luciferase-based bioluminescence imaging offers a non-invasive approach to visualizing and quantifying tumor development across multiple time points. This chapter presents a methodology for employing the IVIS® (in vivo imaging) system to analyze tumor dynamics in luciferase expressing PDX brain tumor models.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/40553291/