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Peer-reviewed veterinary case report

Biphasic malignant melanoma adenocarcinoma in the digit of a dog.

Journal:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Year:
2018
Authors:
Needle, David B et al.
Affiliation:
College of Life Sciences and Agriculture
Species:
dog

Abstract

A 7-y-old Black Russian Terrier dog was evaluated for chronic lameness of the right forelimb and concurrent weight loss. Clinical examination revealed a pigmented mass arising from digit 4 of the right forelimb; the digit was amputated and submitted for histologic evaluation. Histologically, the neoplasm was composed of ill-defined streams, sheets, and clusters of melanocytes admixed with a distinct population of malignant epithelial cells forming glands and nests. The diagnosis was a biphasic malignant melanoma adenocarcinoma, a rarely reported neoplasm in human medicine that has not been described in veterinary medicine, to our knowledge.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29284381/