Peer-reviewed veterinary case report
Blood hyaluronic acid levels linked to cirrhosis in dogs
By Kanemoto, Hideyuki et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Blood hyaluronic acid as a marker for canine cirrhosis.
- Species:
- dog
Plain-English summary
A study found that dogs with liver cirrhosis had higher levels of a substance called hyaluronic acid (HA) in their blood compared to dogs with other liver issues or healthy dogs. Specifically, dogs with cirrhosis had an average HA level of 500 micrograms per liter, while those with non-cirrhotic liver diseases had much lower levels. This suggests that measuring blood HA levels can help veterinarians diagnose liver cirrhosis in dogs. If your dog is showing signs of liver disease, such as jaundice or loss of appetite, discussing a blood test for HA with your vet could be beneficial.
People also search for: dog liver disease symptoms · dog cirrhosis treatment · high hyaluronic acid levels in dogs
Abstract
Blood hyaluronic acid (HA) concentration was measured in dogs with various liver diseases to determine its relationship with histological fibrosis of the liver. The blood HA concentration significantly increased in dogs with chronic liver diseases compared with extrahepatic diseases and control. Furthermore, the median blood HA concentration in dogs with liver cirrhosis (500 microg/l; range, 151-1970 microg/l) was significantly higher than dogs with non-cirrhotic liver diseases (153 microg/l; range, 15-477 microg/l). In histochemical analysis, HA was distributed primarily in the fibrotic area in dogs with chronic liver diseases. As a conclusion, the blood HA concentration was significantly increased in dogs with chronic liver diseases, especially those with cirrhosis. Measurement of the blood HA levels of dogs with suspected liver disease can be a useful diagnostic aid for canine cirrhosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19801910/