Peer-reviewed veterinary case report
Botanicals and Arachidonic Acid Lower Cholesterol and Inflammation
By Jewell, Dennis E & Panickar, Kiran S·Published in Frontiers in veterinary science·2021·Department of Grain Science and Industry, United States·View original on PubMed →
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Original publication title: Botanicals Reduce Circulating Concentrations of Cholesterol and Triglycerides and Work Synergistically With Arachidonic Acid to Reduce Inflammatory Cytokines in Cats.
- Species:
- cat
Plain-English summary
A group of healthy adult cats was fed different diets for 84 days to see how they affected cholesterol, triglycerides, and inflammation. One group received a diet with arachidonic acid (a fatty acid found in animal fats), while another group had a mix of botanicals like green tea and fenugreek. The cats that ate the diet with both arachidonic acid and botanicals showed a significant drop in cholesterol and triglycerides, along with reduced levels of several inflammatory markers. This suggests that combining these ingredients may help lower inflammation and improve overall health in cats.
People also search for: cat cholesterol diet · cat inflammation treatment · arachidonic acid for cats · botanical supplements for cats
Abstract
Forty Eight cats were used to measure the effects of feeding a traditional adult cat food supplemented with either arachidonic acid (ARA), a botanical mix (botanicals) or both on circulating biochemical parameters and inflammatory cytokines. The cats were healthy adults (mean age, 3.0; range, 1.3-6.4 years). The adult cats were fed one of four foods (= 12 per group) for 84 days (dietary changes reported as fed): a traditional adult cat food (control, 0.05% ARA no added botanicals), or control food supplemented with arachidonic acid from chicken liver (0.13% ARA when supplemented), control food supplemented with botanicals (green tea 0.5%, fenugreek 0.05%, and tulsi 0.003%), and control plus ARA (0.13% as fed) with botanicals (green tea 0.5%, fenugreek 0.05%, and tulsi 0.003%). Response variables were compared between treatments: initially, and at 84 days (end of study). The measurements were standard complete blood counts and chemistries as well as circulating cytokines. Botanical inclusion reduced (< 0.05) circulating cholesterol and triglycerides while arachidonic acid increased (< 0.05) their concentrations. The pro-inflammatory cytokines MCP-1, TNFα, SDF-1, Flt3L, IL-8, IL-12p40, IL-13, and IL-18 were all reduced (< 0.05) in cats after consuming the ARA + botanicals food for 84 days with little change after consuming the other foods. Therefore, this combination of ARA and botanicals may be of value in reducing inflammation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33614765/