Peer-reviewed veterinary case report
Bothrops jararacussu snake venom lectin induces mast cell activation and vascular permeability enhance in an animal model.
- Journal:
- Toxicon : official journal of the International Society on Toxinology
- Year:
- 2022
- Authors:
- Kwasniewski, Fábio H et al.
- Affiliation:
- Universidade Estadual de Londrina (UEL) · Brazil
- Species:
- reptile
Abstract
Bothrops species trigger an acute inflammatory response in victims, with activated leukocytes releasing several mediators that may contribute to local and systemic effects. The effects of BjcuL, a lectin isolated from B. jararacussu snake venom, on mast cells and vasopermeability were investigated in this study. BjcuL activates mast cells and increases vasopermeability through the involvement of histamine and platelet activating factor, which may play a role in the victims' acute inflammatory reaction.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34785172/