Peer-reviewed veterinary case report
Botulinum toxin prevents radiotherapy-induced salivary gland damage.
- Journal:
- Oral oncology
- Year:
- 2009
- Authors:
- Teymoortash, Afshin et al.
- Affiliation:
- Department of Otolaryngology · Germany
- Species:
- rodent
Abstract
Radiotherapy of head and neck malignancies results in severe damage to salivary glands. Irradiation-induced sialadenitis with xerostomia leads to a significant deterioration of the quality of life which lasts life-long. Here we show in a preliminary study that intraglandular application of botulinum toxin performed prior to radiation reduces significantly the radiation induced toxicity of the glandular tissue in rats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19213593/