Peer-reviewed veterinary case report
Bridging veins in Alzheimer's disease: Decoding waste clearance failure.
- Journal:
- The Journal of experimental medicine
- Year:
- 2026
- Authors:
- Du, Ting et al.
- Affiliation:
- Department of Neurosurgery · United States
- Species:
- rodent
Abstract
Perivenous tunnels surrounding bridging veins terminate at "arachnoid cuff exit" (ACE) points, which enable waste efflux from the brain. Smyth et al. (https://doi.org/10.1084/jem.20251860) show that amyloid deposits in ACE in Alzheimer's disease mice and human samples identify a potential new therapeutic target.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41369630/