Peer-reviewed veterinary case report
Lung tumor in 5-year-old goat not caused by sheep virus
By Ortín, A et al.·Published in Veterinary pathology·2007·Departamento de Patologí, Spain·View original on PubMed →
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Original publication title: Bronchioloalveolar carcinoma not related to jaagsiekte sheep retrovirus in a goat.
- Species:
- goat
Plain-English summary
A 5-year-old Murciano-Granadina goat was brought in showing signs of weight loss and difficulty breathing. The vet found that the goat was also discharging a lot of white, foamy fluid from its nose. After examining tissue samples, they discovered a lung tumor called bronchioloalveolar carcinoma, which is a type of cancer that starts in the lung's alveolar cells. Tests ruled out any connection to known retroviruses that can cause similar tumors. This case is significant as it shows that this type of lung cancer can occur in goats without being linked to those viruses.
People also search for: goat lung cancer symptoms · why is my goat losing weight · goat breathing problems treatment
Abstract
A spontaneous lung tumor in a 5-year-old goat of the Murciano-Granadina breed is described in this paper. Clinical signs of cachexia and tachypnoea were evident, and a considerable amount of white mucous foamy fluid was discharged from the nostrils when the animal's head was lowered. A lung tumor with the characteristics of bronchioloalveolar carcinoma was detected during histopathologic examination. The tumor cells were positive for surfactant proteins C and B, confirming that alveolar type II cells were the origin of the neoplasia. Tumor samples were tested by polymerase chain reaction, immunoblotting, and immunohistochemistry for the presence of Jaagsiekte sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV), another retrovirus very closely related to JSRV, but all tests were negative. Therefore, this is the first reported case of spontaneous bronchioloalveolar carcinoma not related to JSRV or ENTV infection in a goat.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17846248/