Peer-reviewed veterinary case report
C-reactive protein levels track treatment response in dogs
By Ohno, Koichi et al.·Published in The Journal of veterinary medical science·2006·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: C-reactive protein concentration in canine idiopathic polyarthritis.
- Species:
- dog
Plain-English summary
A group of dogs with idiopathic polyarthritis (a type of joint inflammation with no known cause) had their C-reactive protein (CRP) levels tested to see how it related to their treatment. The dogs showed high CRP levels when diagnosed, but these levels dropped significantly after starting corticosteroid medication, indicating that CRP can help track how well the treatment is working. Six months later, the dogs that continued medication had different CRP levels compared to those that rarely needed it, suggesting that CRP might help predict how a dog will respond to treatment for this condition.
People also search for: dog joint inflammation treatment · idiopathic polyarthritis in dogs · corticosteroids for dog arthritis
Abstract
To investigate the clinical utility of C-reactive protein (CRP) in idiopathic polyarthritis (IPA), its concentration was measured in dogs with IPA. The CRP concentration was markedly increased in all the IPA dogs at the time of diagnosis and decreased significantly in response to the initial corticosteroid treatment; this indicated that CRP can be used as an index for therapeutic response in IPA cases. Furthermore, at 6 months after the diagnosis, a significant association was observed between the CRP concentration at follow-up (6-13 days after the treatment was started) and the frequency of medication ("no or seldom-medicated (NSM)" groups or "continuing medication (CM)" groups). These results suggest that the initial response of CRP to corticosteroid treatment may be a prognostic factor of canine IPA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17213695/