Peer-reviewed veterinary case report
C-reactive protein levels in dogs with chronic heart valve disease
By Rush, John E et al.·Published in Journal of veterinary internal medicine·2006·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: C-reactive protein concentration in dogs with chronic valvular disease.
- Species:
- dog
Plain-English summary
A group of dogs with chronic valvular disease, a common heart problem, showed higher levels of C-reactive protein in their blood compared to healthy dogs. This protein is often a marker of inflammation, and its increased levels suggest that these dogs may be experiencing some underlying issues related to their heart condition. The study involved 47 dogs diagnosed with chronic valvular disease and 20 healthy dogs for comparison. While the exact implications of these findings are still being explored, it highlights the importance of monitoring heart health in dogs with this condition.
People also search for: dog heart disease symptoms · C-reactive protein in dogs · chronic valvular disease in dogs
Abstract
The purpose of the study reported here was to determine whether dogs with chronic valvular disease have increased plasma C-reactive protein concentration, compared with that in clinically normal dogs. Blood was collected from 47 dogs with physical and echocardiographic evidence of chronic valvular disease and from 20 healthy controls. C-reactive protein concentration was determined with a commercial canine C-reactive protein enzyme immunoassay. Compared with controls, dogs with chronic valvular disease had higher plasma concentration of C-reactive protein (median 2.17 microg/mL [range, 0.86-33.8 microg/mL]) versus 1.43 microg/mL [range, 0.84-4.99 microg/mL]; P < .001). C-reactive protein concentration was not related to the presence of congestive heart failure or murmur grade. The results of this study suggest that increased concentration of C-reactive protein is found in dogs with chronic valvular disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16734101/