Peer-reviewed veterinary case report
Caenorhabditis elegans reveals novel Pseudomonas aeruginosa virulence mechanism.
- Journal:
- Trends in microbiology
- Year:
- 2013
- Authors:
- Utari, Putri Dwi & Quax, Wim J
- Affiliation:
- Department of Pharmaceutical Biology · Netherlands
Abstract
The susceptibility of Caenorhabditis elegans to different virulent phenotypes of Pseudomonas aeruginosa makes the worms an excellent model for studying host-pathogen interactions. Including the recently described liquid killing, five different killing assays are now available offering superb possibilities for performing high-throughput screens for novel antibiotics using a whole-body infection system.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23684150/