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Peer-reviewed veterinary case report

New treatments with calcineurin inhibitors for dog skin allergies

By Marsella, Rosanna·Published in Journal of the American Animal Hospital Association·2005·Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610-0126, United States·View original on Crossref

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Original publication title: Calcineurin Inhibitors: A Novel Approach to Canine Atopic Dermatitis

Species:
dog

Plain-English summary

A dog with itchy skin due to atopic dermatitis (a common allergic skin condition) can benefit from new treatments called calcineurin inhibitors, specifically cyclosporine and tacrolimus. These medications have been shown to be effective and well-tolerated, making them a good alternative to traditional treatments like steroids, which can have more side effects. By using these drugs, veterinarians can help manage your dog's skin allergies more safely and effectively.

People also search for: dog itchy skin treatment · atopic dermatitis in dogs · calcineurin inhibitors for dogs

Abstract

The introduction of calcineurin inhibitors represents a major addition to the armamentarium of drugs available to veterinary clinicians for the management of allergic skin diseases. Both cyclosporine and tacrolimus have been proven to be well tolerated and effective for the treatment of atopic dermatitis in dogs. Although broad spectrum in their mechanism of action, they lack the major adverse effects of glucocorticoids and provide an appealing alternative to traditional therapies. The purposes of this article are to review clinically relevant information regarding these agents and to provide tips for maximizing the benefit obtained from these therapies.

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Original publication on Crossref: https://doi.org/10.5326/0410092