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Peer-reviewed veterinary case report

Calcium and magnesium disorders.

Journal:
The Veterinary clinics of North America. Food animal practice
Year:
2014
Authors:
Goff, Jesse P
Affiliation:
Department of Biomedical Sciences · United States

Abstract

Hypocalcemia is a clinical disorder that can be life threatening to the cow (milk fever) and predisposes the animal to various other metabolic and infectious disorders. Calcium homeostasis is mediated primarily by parathyroid hormone, which stimulates bone calcium resorption and renal calcium reabsorption. Parathyroid hormone stimulates the production of 1,25-dihydroxyvitamin D to enhance diet calcium absorption. High dietary cation-anion difference interferes with tissue sensitivity to parathyroid hormone. Hypomagnesemia reduces tissue response to parathyroid hormone.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24980727/