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Peer-reviewed veterinary case report

Cat with calcium oxalate bladder stones and parathyroid cancer

By Marquez, G A et al.·Published in Journal of the American Veterinary Medical Association·1995·Department of Small Animal Clinical Science, United States·View original on PubMed

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Original publication title: Calcium oxalate urolithiasis in a cat with a functional parathyroid adenocarcinoma.

Species:
cat

Plain-English summary

A 9-year-old male domestic shorthair cat was brought to the vet because he was having trouble urinating, not eating, vomiting, and seemed very tired. The vet found a large mass in his neck and discovered high calcium levels in his blood, along with kidney issues and multiple bladder stones made of calcium oxalate. Sadly, the cat was diagnosed with a parathyroid tumor, which was causing these problems. Unfortunately, the cat did not survive, but this case highlights the importance of checking calcium levels in cats with bladder stones to identify underlying issues.

People also search for: cat urinary problems · cat vomiting and lethargy · calcium oxalate stones in cats · cat parathyroid tumor symptoms

Abstract

A 9-year-old castrated male domestic shorthair cat with dysuria, anorexia, vomiting, and lethargy was admitted to the veterinary teaching hospital. A large, firm mass was palpable in the ventral cervical region. Hypercalcemia, azotemia, and nonregenerative anemia were evident on serum biochemical analysis and CBC, and multiple uroliths were detected by abdominal radiography. At necropsy, light microscopy of the ventral cervical mass revealed a parathyroid adenocarcinoma. Light microscopy of sections of the kidneys revealed multifocal, chronic, lymphocytic/plasmacytic, tubulointerstitial nephritis, as well as moderate multifocal acute tubular necrosis. On quantitative analysis, the uroliths were composed of calcium oxalate. Determination of serum calcium concentration is indicated in cats with calcium oxalate urolithiasis to aid in detection of primary hyperparathyroidism.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7759334/