Peer-reviewed veterinary case report
Calcium oxalate bladder stones in young dogs and breeds affected
By Saver, Alexander et al.·Published in The Veterinary record·2021·Department of Medical Sciences, United States·View original on PubMed →
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Original publication title: Calcium oxalate urolithiasis in juvenile dogs.
- Species:
- dog
Plain-English summary
A group of young male French and English Bulldogs, all under 2 years old, were found to have calcium oxalate stones in their urinary tracts. These stones can cause painful urination and other urinary issues. The study showed that these breeds are more likely to develop these stones at a young age compared to other breeds. It suggests that there may be genetic factors at play, especially since most affected dogs were male. If your young Bulldog is showing signs of urinary problems, it's important to consult your vet for proper diagnosis and treatment options.
People also search for: puppy urinary stones treatment · French Bulldog urinary problems · English Bulldog calcium oxalate stones
Abstract
BACKGROUND: The features of juvenile-onset calcium oxalate urolithiasis in dogs have not been previously reported. METHODS: Calcium oxalate urolith submissions to the Minnesota Urolith Center between 2012 and 2016 were analyzed to identify those originating from juvenile (≤2 years, n = 510) or mature (7-9 years, n = 39,093) dogs. Breed, sex, urolith salt type and urolith location were compared between groups. Breeds represented in both groups were also compared with respect to sex, urolith salt type and urolith location. RESULTS: French (odds ratios [OR] = 14.7, p < 0.001) and English (OR = 14.3, p < 0.001) Bulldogs were overrepresented in juvenile submissions. All juvenile French and English Bulldogs were male. Across all breeds, juvenile dogs were more likely to be male (89%, p < 0.001) than mature dogs (79%). Juvenile dogs were also more likely to form dihydrate stones compared to mature dogs (33% versus 14%, respectively; p < 0.001). Breed differences were discovered in sex, urolith salt type and stone location. CONCLUSIONS: French and English Bulldogs comprise a greater proportion of juvenile calcium oxalate urolith submissions than expected based on their rarity in mature submissions. Inherited risk factors, particularly X chromosome variants, should be investigated due to the strong breed and sex predispositions identified.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34357620/