Peer-reviewed veterinary case report
Calf form bovine leukosis with lameness in a Holstein heifer.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2012
- Authors:
- Tawfeeq, Mohammad Monir et al.
- Affiliation:
- Department of Clinical Veterinary Medicine · Japan
Abstract
A 12-month-old Holstein heifer with anorexia, lameness, and enlargement of peripheral lymph nodes was suspected of having bovine leukosis. Although lymphocytosis was not observed, cytology of fine needle aspirate from a superficial cervical node, and increased serum lactate dehydrogenase and thymidine kinase activities, strongly suggested lymphosarcoma. Increased numbers of mononuclear cells as well as mitotic cells were observed in synovial fluid collected from swollen joints. Pathological examination confirmed B-cell calf form bovine leukosis and joint swelling related to neoplastic cell infiltration. Both interleukin-2 receptor and thymidine kinase 1 genes were highly expressed in cells from superficial cervical lymph node aspirate.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22673599/