Peer-reviewed veterinary case report
Herpesvirus disease in 9-week-old Bulldog puppies and virus shedding
By Kapil, Sanjay·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2015·Oklahoma Animal Disease Diagnostic Laboratory·View original on PubMed →
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Original publication title: Canid herpesvirus 1 (CHV-1)-related disease in older puppies and CHV-1 shedding in the vagina of adult pregnant dogs.
- Species:
- dog
Plain-English summary
A group of Bulldogs at a breeding kennel in Arkansas had ongoing issues with Canid herpesvirus 1 (CHV-1), which caused health problems in older puppies around 9 weeks old. Despite the adult dogs having high levels of antibodies against the virus, CHV-1 continued to spread among the dogs in the kennel for over three years. Testing confirmed the presence of the virus in tissue samples, indicating that it was still active in the environment. This situation highlights the importance of monitoring and managing viral infections in breeding facilities to protect the health of puppies.
People also search for: Bulldog puppy health problems · Canid herpesvirus in dogs · puppy virus symptoms · how to prevent puppy infections
Abstract
A large breeding kennel of Bulldogs (n = 57) experienced several Canid herpesvirus 1 (CHV-1)-related diseases in older puppies (9 weeks of age) in Arkansas. CHV-1 has been repeatedly confirmed in the kennel in several animals for 3 years (January 2012-February 2015) using various virology tests. I was able to detect a partial sequence of CHV DNA (~120 bp) in archived formalin-fixed, paraffin-embedded tissue blocks after 3 years of storage. CHV-1 is persistently circulating in this kennel in spite of high serum antibody titers in the adult dogs. The dogs were negative for canine brucellosis antibodies based on Brucella canis rapid card test.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26450840/