Peer-reviewed veterinary case report
Puppy with fever and wasting died from adenovirus and Pasteurella
By Pintore, Maria Domenica et al.·Published in Veterinaria italiana·2016·Istituto Zoopro lattico Sperimentale del Piemonte, Italy·View original on PubMed →
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Original publication title: Canine adenovirus type 1 and Pasteurella pneumotropica co‑infection in a puppy.
- Species:
- dog
Plain-English summary
A 2-month-old male German Shepherd puppy was brought to the vet with a fever, depression, and noticeable weight loss. Sadly, the puppy passed away within 48 hours of showing these symptoms. A thorough examination revealed that the puppy was infected with both canine adenovirus type 1 and Pasteurella pneumotropica, a bacteria that can cause severe illness. The findings suggest that the viral infection may have weakened the puppy's immune system, allowing the bacteria to cause further complications. Unfortunately, despite the veterinary efforts, the puppy did not survive.
People also search for: puppy fever and depression · German Shepherd puppy illness · canine adenovirus symptoms · Pasteurella infection in dogs
Abstract
In 2008, a 2 months-old male German shepherd was presented with fever, depression, and evident organic wasting. The puppy died within 48 hours after the onset of clinical signs. A complete necropsy was performed. Bacteriological examination of samples from the brain, lung, liver, spleen, and bone marrow tested positive for Pasteurella pneumotropica. Histopathology demonstrated inflammatory and vascular lesions in the central nervous system and internal organs. Canine adenovirus type 1 nucleic acid was detected by polymerase chain reaction in the frozen brain but not in the formalin-fixed, paraffin-embedded liver and lung samples. The positive PCR was subsequently confirmed by indirect fluorescent antibody testing of the paraffin-embedded brain and liver sections. Although the liver is the primary site of viral damage, these laboratory findings suggest that Canine adenovirus type 1 infection should be included in the differential diagnosis of neuropathological diseases in dogs and that adenoviral infections could promote septicaemia caused by opportunistic pathogens.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27033531/