Peer-reviewed veterinary case report
Puppy with neurological signs caused by canine adenovirus 1
By Hornsey, Samuel J et al.·Published in BMC veterinary research·2019·Department of Clinical Sciences, Canada·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Canine adenovirus type 1 causing neurological signs in a 5-week-old puppy.
- Species:
- dog
Plain-English summary
A 5-week-old male Husky cross puppy was brought to the vet with unusual neurological symptoms, including circling, difficulty walking, and vocalizing. Unfortunately, the puppy's condition worsened quickly, and he was euthanized shortly after arriving at the clinic. Tests revealed that he had a severe infection caused by Canine Adenovirus-1, which is rare but can lead to neurological issues in young, unvaccinated dogs. This case highlights the importance of vaccination and awareness of potential infections that can affect a puppy's nervous system.
People also search for: puppy neurological signs · Canine Adenovirus-1 symptoms · unvaccinated puppy illness · puppy circling behavior · canine hepatitis treatment
Abstract
BACKGROUND: Infectious canine hepatitis is a rarely encountered disease, that is caused by Canine Adenovirus-1. Clinical signs can vary dramatically, and neurological signs are rarely seen. Neurological manifestation of this disease is rarely reported in the veterinary literature. CASE PRESENTATION: A 5-week-old, male entire Husky cross puppy presented for a one-day history of abnormal neurological behaviour (circling, ataxia, vocalization and obtund mentation). The puppy was euthanized shortly after presentation due to rapid deterioration. Histopathology raised concerns for Canine Adenovirus 1 (CAdV-1) based on vasculitis in the brain and intranuclear inclusion bodies in endothelial cell and hepatocytes; immunohistochemistry on brain tissue confirmed CAdV-1 infection. CONCLUSIONS: This report discusses possible routes of infection and manifestations of adenovirus infections causing neurologic signs. It also provides a timely reminder that CAdV-1 should be considered a differential in unvaccinated dogs that present with neurological signs. Further studies are required to better understand the neurotrophic tendencies of this virus.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31752890/