Peer-reviewed veterinary case report
Puppies with neurological signs from canine adenovirus type 2
By Benetka, V et al.·Published in The Veterinary record·2006·Institute of Virology·View original on PubMed →
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Original publication title: Canine adenovirus type 2 infection in four puppies with neurological signs.
- Species:
- dog
Plain-English summary
Four puppies, aged 9 to 11 weeks, showed signs of respiratory issues and neurological problems due to an infection with canine adenovirus type 2. Unfortunately, three of the puppies had to be euthanized. They were found to have pneumonia, but their brains showed no significant damage. Tests confirmed the presence of the virus in their lungs, and a bacterial infection was also found. Sadly, the outcome was not favorable for these puppies, highlighting the seriousness of this viral infection.
People also search for: puppy respiratory problems · canine adenovirus symptoms · puppy neurological signs · Bordetella bronchiseptica in dogs
Abstract
Four nine- to 11-week-old puppies developed respiratory and neurological signs due to an infection with canine adenovirus type 2 (cav-2); three of these were euthanased. They had moderate, diffuse pneumonia but there were no histological abnormalities in the central nervous system. Adenovirus-specific nucleic acid was detected by pcr in samples of lung and brain and the amplified product was 99.8 per cent homologous with the cav-2 reference strain Toronto a26/61. The positive pcr result was confirmed by in situ hybridisation in samples of lung, liver and spleen, but not in brain, and cav was isolated in cell culture from lung material; pcrs for canine distemper virus and canine herpesvirus-specific nucleic acids were negative, but large amounts of Bordetella bronchiseptica were isolated from lung material.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16428663/