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Peer-reviewed veterinary case report

Canine and Feline Cutaneous Epitheliotropic Lymphoma and Cutaneous Lymphocytosis.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2019
Authors:
Rook, Kathryn A
Affiliation:
Department of Clinical Sciences and Advanced Medicine · United States

Plain-English summary

Cutaneous lymphomas are a type of cancer that affects the skin in dogs and cats. There are different types based on how the cancer cells behave and where they are found in the skin. One type, called epitheliotropic cutaneous lymphoma (or cutaneous T-cell lymphoma), occurs when cancer cells invade the outer layer of the skin. Another related condition is cutaneous lymphocytosis, which is a slower-growing form of lymphoma. This article mainly discusses these two conditions and how they are diagnosed in pets.

Abstract

Cutaneous lymphomas are divided into categories based on histologic evaluation of the skin and location of neoplastic lymphocytes. Epitheliotropic cutaneous lymphoma, also known as cutaneous T-cell lymphoma, is diagnosed when neoplastic lymphocytes show tropism for the epidermis and these cells infiltrate the epidermis and adnexae. In diagnosis of nonepitheliotropic cutaneous lymphoma, neoplastic lymphocytes are found mostly in the dermis and/or subcutis. Neoplastic cells are of either B-cell or T-cell origin. This article focuses on epitheliotropic cutaneous lymphomas and cutaneous lymphocytosis, which is considered a form of indolent lymphoma, in dogs and cats.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30262145/