Peer-reviewed veterinary case report
Anal sac gland cancer in dogs - signs and treatment options
By Repasy, Alec B et al.·Published in Topics in companion animal medicine·2022·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Canine Apocrine Gland Anal Sac Adenocarcinoma: A Review.
- Species:
- dog
Plain-English summary
A dog with anal gland cancer, known as apocrine gland anal sac adenocarcinoma, can show symptoms like difficulty defecating or swelling around the rear end due to the tumor or nearby lymph nodes. The best treatment usually involves surgically removing the tumor and any affected lymph nodes, and sometimes radiation or chemotherapy is added to help. Dogs with smaller tumors tend to have better outcomes and can live longer with proper treatment. If you notice any unusual signs around your dog's rear, it's important to consult your veterinarian for a thorough evaluation.
People also search for: dog anal gland cancer symptoms · treatment for dog anal sac adenocarcinoma · dog difficulty defecating · dog swollen lymph nodes near anus
Abstract
Apocrine gland anal sac adenocarcinoma (AGASAC) is a relatively uncommon tumor in the dog and comprises approximately 17% of perianal malignancies; however, it is one of the most common causes of paraneoplastic hypercalcemia. Clinical signs in affected dogs most commonly are associated with mechanical obstruction caused by the primary tumor or enlarged regional metastatic lymph nodes and the effects of paraneoplastic hypercalcemia when present. Surgical excision of the primary tumor and metastasectomy of affected locoregional lymph nodes is the preferred initial treatment option for most dogs, although radiation therapy and adjuvant chemotherapy are commonly incorporated into multi-modality treatment plans. A significant role for the use of adjuvant chemotherapy has not been clearly demonstrated. Prolonged survival times are possible, especially for dogs with smaller primary tumors and for dogs that undergo further treatments for recurrent disease. In this article, we review the clinical signs, diagnosis, staging, treatment, and prognosis of AGASAC in the dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35792243/