Peer-reviewed veterinary case report
Natural luteolin treatment for dog skin allergy (atopic dermatitis)
By Gugliandolo, Enrico et al.·Published in Veterinary Medicine and Science·2020·Department of Chemical Biological, Pharmaceutical and Environmental Sciences University of Messina Messina Italy, Italy·View original on Crossref →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Canine atopic dermatitis: Role of luteolin as new natural treatment
- Species:
- dog
Plain-English summary
A study explored the potential of luteolin, a natural compound, as a treatment for dogs suffering from atopic dermatitis, which causes itchy skin. In laboratory tests, luteolin showed promise by reducing inflammation markers associated with this skin condition. While this research is still in the early stages, it suggests that luteolin could be a beneficial option for managing atopic dermatitis in dogs. If your dog has skin problems, discussing luteolin with your veterinarian might be worthwhile.
People also search for: dog itchy skin treatment · natural remedies for dog dermatitis · luteolin for dogs skin problems
Abstract
AbstractBackgroundLuteolin has been demonstrated to possess numerous biological effects. However, the effect of luteolin on LPS (Lipopolysaccharides) stimulation in CPEK cells has not been investigated.Hypothesis/ObjectivesAn in vitro model of atopic canine dermatitis was used to identify the antioxidant effect of luteolin as a new treatment that is capable of improving the conditions of veterinary patients.MethodsCPEK cells were treated with or without luteolin in the presence or absence of LPS. A cell viability assay was performed to test luteolin toxicity and the protective effect of luteolin after LPS stimulation. Additionally, enzyme‐linked immunosorbent assay (ELISA) kits were used to detect the levels of IL‐33, IL‐1β, IL‐6, and IL‐8.ResultsLuteolin was capable to significantly decrease levels expression of IL‐33, IL 1β, IL‐6, and IL‐8.Conclusions and clinical importanceLuteolin could be a new pharmacological treatment for canine atopic dermatitis.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Crossref: https://doi.org/10.1002/vms3.325