Peer-reviewed veterinary case report
Dog breeds at high risk of inflammatory bowel disease in SE UK
By Kathrani, A et al.·Published in The Veterinary record·2011·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
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Original publication title: Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK.
- Species:
- dog
Plain-English summary
A study found that certain dog breeds in the south-eastern UK are at a higher risk of developing inflammatory bowel disease (IBD), which can cause symptoms like vomiting, diarrhea, and weight loss. The breeds most affected include Weimaraners, Rottweilers, German Shepherds, Border Collies, and Boxers. Understanding which breeds are more susceptible to IBD can help veterinarians and researchers focus on genetic factors that may contribute to this condition. If you have one of these breeds and notice any digestive issues, it's a good idea to consult your veterinarian for advice and possible testing.
People also search for: dog vomiting treatment · German Shepherd IBD symptoms · Rottweiler digestive problems
Abstract
Genetics are an important factor in the development of human inflammatory bowel disease (IBD); however, there is very little information available regarding the role of genetics in canine IBD. The purpose of this study was to gather information about which canine breeds in the south-eastern UK are at a high risk for developing IBD. Determination of such breeds may help further genetic research in this complex disease. The computer medical records at the Queen Mother Hospital for Animals, Royal Veterinary College dating from August 1, 2003 to December 31, 2009 were retrospectively searched for cases diagnosed with IBD. Five hundred and forty-six dogs with IBD were identified, representing 86 different breeds. The comparison group consisted of all dogs from these same 86 breeds without IBD admitted to the hospital during the same period that amounted to 27,463 dogs. The breeds at significantly higher risk of developing IBD compared with mixed-breed dogs consisted of weimaraner (odds ratio [OR]=3.6797, 95 per cent confidence interval [CI]=2.0167 to 6.7141, P<0.0001), rottweiler (OR=2.9697, 95 per cent CI=1.7569 to 5.0196, P<0.0001), German shepherd dog (GSD) (OR=2.4101, 95 per cent CI=1.5826 to 3.36705, P<0.0001), border collie (OR=1.9936, 95 per cent CI=1.1655 to 3.4101, P=0.0118) and boxer (OR=1.6961, 95 per cent CI=1.0441 to 2.755, P=0.0328). This study demonstrates for the first time canine breeds in the south-eastern UK that are highly susceptible to developing IBD. Identification of such breeds may allow for a more focused investigation of genetic mutations associated with canine IBD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21896567/