Peer-reviewed veterinary case report
Dog in Connecticut died from canine circovirus causing bleeding
By Van Kruiningen, Herbert J et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2019·Department of Pathobiology and Veterinary Science·View original on PubMed →
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Original publication title: Canine circoviral hemorrhagic enteritis in a dog in Connecticut.
- Species:
- dog
Plain-English summary
A 5-month-old Bassett Hound-Labrador mix was found to be very lethargic, not eating, and had bleeding gums. Sadly, the dog passed away, and an autopsy revealed severe damage to the intestines and other organs, along with signs of a viral infection. The cause was identified as circovirus, which led to inflammation and bleeding in various parts of the body. Unfortunately, there was no treatment that could save the dog, highlighting the seriousness of this viral infection.
People also search for: dog lethargy and bleeding gums · circovirus in dogs · puppy intestinal bleeding treatment
Abstract
A 5-mo-old Bassett Hound-Labrador Retriever cross was autopsied following a bout of lethargy, inappetence, and bleeding gums. Mucous membranes were white, and the small intestine was blue-black; the colon contained black feces. The spleen was swollen, and multiple lymph nodes were enlarged and hemorrhagic. Microscopically, the small intestine had focal crypt cell necrosis and circumferential transmural vasculitis, the latter the cause of infarction and the blue-black coloration. Lymphocytes were necrotic in spleen and lymph nodes, and erythrophagocytosis was present in some nodes. Vasculitis was present in brain, meninges, lung, liver, and kidneys. Electron microscopy revealed aggregates of 15-18 nm round viral particles in damaged crypt cells and in the endothelium of small blood vessels. Electron-dense intracytoplasmic inclusions consisting of paracrystalline-arrayed virus were demonstrated in macrophages in medullary lymph node sinuses. These virions were identified as circovirus, which was confirmed by real-time PCR and sequencing.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31291838/