Peer-reviewed veterinary case report
Fluorescent test predicts recovery in vaccinated dogs
By Kapil, Sanjay & Neel, Tina·Published in Journal of clinical microbiology·2015·Oklahoma Animal Disease Diagnostic Laboratory, United States·View original on PubMed →
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Original publication title: Canine distemper virus antigen detection in external epithelia of recently vaccinated, sick dogs by fluorescence microscopy is a valuable prognostic indicator.
- Species:
- dog
Plain-English summary
A group of recently vaccinated dogs in Oklahoma City developed respiratory disease and were tested for canine distemper virus (CDV) using a special fluorescent antibody test. The results showed that dogs with negative CDV test results had an 80% chance of recovery after standard treatment, while those with positive results had only a 55% chance. This test helps veterinarians predict which dogs are more likely to recover, allowing for better treatment decisions and potentially avoiding unnecessary euthanasia.
People also search for: dog respiratory disease treatment · canine distemper virus symptoms · vaccinated dog sick prognosis
Abstract
Currently, there are no reliable predictors of the clinical outcomes of domesticated dogs that have been recently vaccinated against canine distemper virus (CDV) and develop respiratory disease. In this study, vaccinated dogs from Oklahoma City that were showing clinical signs of respiratory disease were evaluated for CDV antigen using a direct fluorescent antibody test (FAT). Clinical outcomes after standard symptomatic therapy for respiratory disease were recorded, and a statistical analysis of the results was performed. We present our study showing that CDV FAT results were predictive of clinical recovery (prognostic indicator, prospects of clinical recovery) among vaccinated dogs showing clinical signs of respiratory disease. Negative CDV FAT results equated to 80% chances of recovery after symptomatic therapy, compared to 55% chances of recovery when the CDV FAT results were positive. Based on the results of this study, we show that veterinarians can make better informed decisions about the clinical outcomes of suspected CDV cases, with 2-h turnaround times, by using the CDV FAT. Thus, antemortem examination with the CDV FAT on external epithelia of recently vaccinated, sick dogs is a clinically useful diagnostic test and valuable prognostic indicator for veterinarians. Application of the CDV FAT to these samples avoids unnecessary euthanasia of dogs with suspected CDV.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25428156/