Peer-reviewed veterinary case report
Heart function and treatment outcomes in dogs with left ventricular
By Loureiro, J et al.·Published in The Journal of small animal practice·2008·The Scarsdale Veterinary Hospital, United Kingdom·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Canine dynamic left ventricular outflow tract obstruction: assessment of myocardial function and clinical outcome.
- Species:
- dog
Plain-English summary
A young dog with a heart murmur was diagnosed with dynamic left ventricular outflow tract obstruction, a condition affecting how blood flows out of the heart. The dog was treated with a beta-blocker, which helped reduce the heart's workload. After treatment, the dog's heart showed improvement, including a decrease in heart muscle thickening and resolution of the obstruction. This suggests that with proper treatment, dogs with this condition can see significant recovery.
People also search for: dog heart murmur treatment · dynamic left ventricular outflow tract obstruction in dogs · beta-blocker for dog heart problems
Abstract
OBJECTIVE: The aims of this study were (i) to evaluate echocardiographic findings and myocardial function including pulsed wave tissue Doppler imaging in dogs with naturally occurring dynamic left ventricular outflow tract obstruction and (ii) to investigate the clinical outcome and response to therapy in these dogs. METHODS: Two cases were retrospectively reviewed and three cases were prospectively evaluated including clinical findings, diagnostic test results (including standard Doppler echocardiography and pulsed wave tissue Doppler imaging), response to treatment and outcome. The two retrospective cases received no treatment. Other cases were treated with a beta-blocker. RESULTS: All dogs had a variable intensity left apical systolic murmur. Concentric left ventricular hypertrophy, systolic anterior motion of the mitral valve and scimitar-shaped left ventricular outflow tract Doppler flow profile were present in all cases. Pulsed wave tissue Doppler imaging interrogation of the interventricular septum revealed E'/A' reversal in all but one patient. Regression of left ventricular hypertrophy and total resolution of the dynamic left ventricular outflow tract obstruction were observed in all cases. CLINICAL SIGNIFICANCE: Young dogs are affected with a possible terrier breed predisposition. Dynamic left ventricular outflow tract obstruction may be distinguished from canine hypertrophic cardiomyopathy as progressive resolution of echocardiographic abnormalities was documented. Pulsed wave tissue Doppler imaging abnormalities provide further evidence for significant diastolic dysfunction associated with the hypertrophy.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18684141/