Peer-reviewed veterinary case report
Canine glioma in the first year of life: 5 cases.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2024
- Authors:
- Dos Santos, Esdras C et al.
- Affiliation:
- Department of Pathology · United States
- Species:
- dog
Plain-English summary
This study looked at five young dogs, all under a year old, that were diagnosed with gliomas, which are brain tumors. The dogs, four males and one female, showed signs like being less alert, having seizures, and in one case, trouble with balance and hearing. Unfortunately, all of these dogs were euthanized due to the severity of their condition. The tumors were found in different parts of the brain and were identified as two types of gliomas. This research highlights that while it's very rare, young dogs can develop these serious tumors similar to those seen in older dogs.
Abstract
Most canine gliomas occur in adult and aged dogs, and reports in puppies < 12-mo-old are exceedingly rare. Here we describe the occurrence of gliomas in 5 dogs ≤ 12-mo-old. The affected patients (4 males, 1 female) were 3-12-mo-old (x̄ = 6.6-mo-old). None of the dogs were brachycephalic. Clinical signs consisted of dullness (2 cases), seizures (2 cases), vestibular signs, and deafness (1 case each). All patients were euthanized. Grossly, neoplasms were pale-tan or red, soft masses in the telencephalon (4 cases) or gelatinous leptomeningeal thickening in the brain and spinal cord (1 case). Neoplasms were classified as astrocytomas (3 cases) and oligodendrogliomas (2 cases) based on histology or histology and IHC. Our findings confirm that, while exceptionally rare, canine gliomas occur in the first year of life, and are clinically, morphologically, and immunohistochemically similar to gliomas in adult and aged dogs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38561905/