Peer-reviewed veterinary case report
Joint damage in Beagles with bleeding factor deficiencies seen on MRI
By Pownder, Sarah L et al.·Published in Veterinary and comparative orthopaedics and traumatology : V.C.O.T·2026·Hospital for Special Surgery, United States·View original on PubMed →
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Original publication title: Canine Haemophilic Arthropathy: Magnetic Resonance Imaging and Histologic Assessment of Joints in Two Adult Beagles with Confirmed Factor Deficiencies.
- Species:
- dog
Plain-English summary
Two adult female Beagle dogs were examined for joint problems caused by a bleeding disorder known as haemophilic arthropathy (HA). One dog had a severe case due to Factor IX deficiency, while the other had only mild issues from Factor VII deficiency. Both dogs showed signs of joint damage similar to what humans experience, including cartilage wear and inflammation. The study found that using magnetic resonance imaging (MRI) can help veterinarians identify these joint issues in dogs that have had repeated bleeding episodes.
People also search for: Beagle joint problems · dog bleeding disorder treatment · haemophilic arthropathy in dogs
Abstract
Two adult female Beagle dogs, one case each of hereditary Factor VII deficiency and Factor IX deficiency, were evaluatedfor joint pathology associated with haemophilic arthropathy (HA) using magnetic resonance imaging and histology. Cadaveric magnetic resonance imaging and histologic findings demonstrated severe HA for the Factor IX deficiency dog, with only mild abnormalities for the Factor VII deficiency dog. Signs of HA were similar to humans, including cartilage degeneration, subchondral cysts, peripheral erosions, neovascularization, synovial inflammation and hyperplasia, hemosiderin deposition, haematoma and osteoporosis. Magnetic resonance imaging examination can be used to help identify features of HA in dogs that have experienced repeated joint bleeds.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40719108/